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NHG Health Office of Human Research Protection Programme (OHRPP)

NHG Health Research Policies and Guidelines

Read the key policies and guidelines every NHG Health researcher must know before starting a study. Download manuals, SOPs, and policies covering research ethics, data governance, and tissue banking.

Last updated 8 July 2026

Policies & Guidelines that Researchers should know

Prior to starting your research, we urge all researchers to familiarize themselves with the following policies/guidelines:

NHG Health Responsible Conduct of Research (RCR) Manual

As part of the NHG Health Office of Human Research Protection Programme (OHRPP)’s effort to promote the Responsible Conduct of Research (RCR) awareness within our research community, we have put together this manual so that researchers will be better equipped with knowledge about RCR and be better prepared to deal with any integrity dilemma that they will invariably encounter in their daily research activities and research career. The RCR Manual will provide researchers with insights to the outlines of the overall governance of research, provides procedural guidelines for meeting ethical requirements in research, and offer guidance on key ethical issues.

NHG Health Investigator’s Manual

To ensure that our growing pool of PIs understand research ethics meaningfully, the NHG Health Investigator’s Manual is a handy reference tool catering to both new and experienced investigators alike.

This publication amalgamated the regulatory requirements, NHG Health DSRB research policies and institutional policies governing research conduct, allowing PIs to adeptly navigate the formidable convolutions of the research maze. The Investigator’s Manual is both practical and useful and you will actively use it to improve the ethical standards of your research.

NHG Health Proper Conduct of Research (PCR) SOPs and Templates

The NHG Health PCR SOPs and Templates are developed by NHG Health Group Research & Innovation to provide detailed procedures on conducting research in accordance with applicable guidelines and regulations.

NHG Health Research Institution Policy

The NHG Health Research Institution (RI) Policy outlines the functions and duties of NHG Health RI and duties of the NHG Health Principal Person-In-Charge (PIC) to fulfill the requirements of the HBRA and describes the NHG Health research governance framework that enables the RI to meet the requirements of the HBRA and other relevant Acts and regulations applicable to research.

NHG Health Research Data Policy

The NHG Health Research Data Policy provides the framework for governing research data to ensure compliance with the HBRA, Personal Data Protection Act (PDPA), Healthtech Instruction Manual (HIM), Synapxe policies and all other relevant regulations.

NHG Health Human Tissue Bank Policy

The purpose of the NHG Health Human Tissue Bank Policy is to outline the definitions, the establishment, ethical consideration, ownership, governance and management of the NHG Health tissue banks for research to ensure that tissue banking activities are in accordance with the requirements of the Human Biomedical Research Act (HBRA).

Suggested Readings & References

  • Declaration of Helsinki (opens in new tab)
    Developed by the World Medical Association (WMA), the Declaration of Helsinki is a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and data.

  • Guidance by the Bioethics Advisory Committee (BAC) (opens in new tab)
    The Bioethics Advisory Committee (BAC) was established by the Singapore Cabinet in December 2000. It has been tasked to address the ethical, legal and social issues arising from biomedical sciences research in Singapore. The BAC actively gathers information and views from the international and local community, and after careful deliberation, makes recommendations to the Singapore Government on the regulation of human biomedical research.

  • Ministry of Health (MOH) - Human Biomedical Research Act (HBRA) (opens in new tab)
    The Singapore Human Biomedical Research Act (HBRA) provides clarity regarding the roles and responsibilities of individuals and body corporates involved in human biomedical research and the handling of human tissue for use in research. Through the legislation, the Ministry of Health (MOH) strives to ensure that human biomedical research and tissue banking activities carried out in Singapore follow the law and principles of good clinical practice relating to ethics and science to protect the safety and welfare of research subjects and tissue donors.