NHG Investigator's Manual

About the NHG Investigator's Manual

The NHG Investigator's Manual is an amalgamation of the regulatory requirements, NHG DSRB research policies and institutional policies governing research conduct, allowing PIs to adeptly navigate the formidable convolutions of the research maze.

The latest Fourth Edition of the Investigator’s Manual includes the regulatory requirements (especially the revised regulatory framework for clinical trials), ethical provisions and institutional policies governing research conduct for Investigators, Researchers & Study Administrators.

• Download the NHG Investigator’s Manual - All that an Investigator Needs to Know (4th Edition) here.

Summary of Updates

• Download the Summary of Changes to the NHG Investigator Manual here (Last updated: 21 Nov 2023).

Individual Chapters

Alternatively, you may choose to download the individual Chapters of the above NHG Investigator’s Manual which are of interest.

• Cover & Foreword

• Content Page

• Chapter 1 - Research Governance 

• Chapter 2 - Regulation Requirements 

• Chapter 3 - The Study Team 

• Chapter 4 - Submission to DSRB 

• Chapter 5 - Informed Consent 

• Chapter 6 - Vulnerable Population

• Chapter 7 - Study Conduct 

• Chapter 8 - Standing Database 

• Chapter 9 - Tissue Repository